By Malcolm Higgins
ISBN-10: 0153640642
ISBN-13: 9780153640643
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Sample text
Veterinarians began prescribing a number of drugs for a wide variety of behavior problems. Unfortunately, in many cases, a specific diagnosis is never determined. Consequently, even with improvement of the animal’s behavior, it is difficult to predict what situations are best suited for that drug. In veterinary medicine, there has always been a tendency to try a new behavior drug to treat all types of problem behaviors. In the past, however, there was usually only a single drug to try. Today there are a large number of human psychotropic drugs available from a variety of pharmacologic classifications.
Vet Med 1994; 89(10):960. Dodman NH, Shuster L (eds): Psychopharmacology of Animal Behavior Disorders. Malden, MA: Blackwell Science, 1988. Duxbury MM, Jackson JA, Line SW, et al: Puppy socialization class attendance and other factors related to postweaning handling: The association with retention of dogs in their homes. AVSAB Annual Symp Anim Behav Res 2002 Meeting Proc, 2002:4. Duxbury MM, Jackson JA, Line SW, et al: Evaluation of association between retention in the home and attendance at puppy socialization classes.
Monoamine oxidase (MAO) is found in many body tissues, so most of the inhibitor drugs are nonspecific. 44,140 In presynaptic neurons, MAO is a mitochondrial enzyme involved in the deamination of catecholamines. This deamination in turn reduces production of the neurotransmitter. 125,140,263,288 Both types share dopamine and tyramine as substrates. MAO-A selectively metabolizes or, if present in large amounts, blocks serotonin and norepinephrine. 125,263,285 The newer MAOIs have a higher affinity for either type A or type B.
If You Want a Pet by Malcolm Higgins
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